NOTICE OF BUSINESS CLOSURE

Dear Valued Customers, Partners, and Stakeholders,

AIE Pharmaceuticals, Inc. shut its doors in February 2024 and was officially terminated in April 2025.

We express our deepest gratitude for your support, trust, and partnership over the years. It has been our privilege to serve you.

Please be advised that AIE has not sold, transferred, or assigned any of its intellectual property, domain names, licenses, certifications, or permits to any third parties. All such assets are either expired, terminated, or remain the sole property of Dr. Youssef’s estate and are not available for use or acquisition.

Thank you once again for your patronage and understanding.